1. n. an overdose of a drug. (Initialism. Drugs.)□ Bart took an OD and was sent to the hospital.□ If you take an OD and no one is around, you may end up dead.2. in. to purposely or accidentally give oneself a fatal dose of drugs. (Drugs.)□ Bart ODed on heroin.□ I knew he would OD someday.3. in. to die from an overdose of drugs. (Drugs.)□ Two kids at my school ODed last weekend.□ I think Max may OD in a week or two.4. n. a person who has taken an overdose of drugs. (Hospitals.)□ This OD has just stopped breathing.□ How many ODs did you get in here last weekend?
Dictionary of American slang and colloquial expressions. 2015.